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Glu-286 Rotation and Water Wire Reorientation Are Unlikely the Gating Elements for Proton Pumping in Cytochrome c Oxidase

One of the key unresolved issues regarding proton pumping in cytochrome c oxidase (CcO) is the identity of the gating element that prevents the backflow of protons. In this study, we analyze two popular proposals for this element: isomerization of the key branching residue (Glu-286) and (re)orientat...

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Bibliografski detalji
Glavni autori: Yang, Shuo, Cui, Qiang
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127198/
https://ncbi.nlm.nih.gov/pubmed/21723815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.05.004
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