Molecular determinants of PI3Kγ-mediated activation downstream of G-protein–coupled receptors (GPCRs)

Phosphoinositide 3-kinase gamma (PI3Kγ) has profound roles downstream of G-protein–coupled receptors in inflammation, cardiac function, and tumor progression. To gain insight into how the enzyme’s activity is shaped by association with its p101 adaptor subunit, lipid membranes, and Gβγ heterodimers,...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Vadas, Oscar, Dbouk, Hashem A., Shymanets, Aliaksei, Perisic, Olga, Burke, John E., Abi Saab, Widian F., Khalil, Bassem D., Harteneck, Christian, Bresnick, Anne R., Nürnberg, Bernd, Backer, Jonathan M., Williams, Roger L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2013
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839701/
https://ncbi.nlm.nih.gov/pubmed/24190998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304801110
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia