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Survivin Mediates Renal Proximal Tubule Recovery from AKI

AKI induces the renoprotective upregulation of survivin expression in kidney epithelial cells, but the underlying mechanisms have not been identified. To determine the role of survivin in renal recovery from AKI, we generated mice with renal proximal tubule-specific deletion of survivin (survivin(pt...

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Autors principals: Chen, Jianchun, Chen, Jian-Kang, Conway, Edward M., Harris, Raymond C.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839548/
https://ncbi.nlm.nih.gov/pubmed/23949800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013010076
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