Na(+)/HCO(3)(–) Cotransporter NBCn2 Mediates HCO(3)(−) Reclamation in the Apical Membrane of Renal Proximal Tubules

The kidney maintains systemic acid-base balance by reclaiming from the renal tubule lumen virtually all HCO(3)(−) filtered in glomeruli and by secreting additional H(+) to titrate luminal buffers. For proximal tubules, which are responsible for about 80% of this activity, it is believed that HCO(3)(...

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Bibliographische Detailangaben
Veröffentlicht in:J Am Soc Nephrol
Hauptverfasser: Guo, Yi-Min, Liu, Ying, Liu, Mei, Wang, Jin-Lin, Xie, Zhang-Dong, Chen, Kang-Jing, Wang, Deng-Ke, Occhipinti, Rossana, Boron, Walter F., Chen, Li-Ming
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2017
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533233/
https://ncbi.nlm.nih.gov/pubmed/28280139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016080930
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