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Kinetic and Isotopic Characterization of L-Proline Dehydrogenase from Mycobacterium tuberculosis

The monofunctional proline dehydrogenase (ProDH) from Mycobacterium tuberculosis performs the flavin-dependent oxidation of L-proline to Δ(1)-pyrroline-5-carboxylate (P5C) in the proline catabolic pathway. The ProDH gene, prub, was cloned into the pYUB1062 vector, and the C-terminal His-tagged 37 kD...

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Detalhes bibliográficos
Main Authors: Serrano, Hector, Blanchard, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839249/
https://ncbi.nlm.nih.gov/pubmed/23834473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400338f
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