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Kinetic Characterizations of Nitrocefin, Cefoxitin, and Meropenem Hydrolysis by β-lactamase from Mycobacterium tuberculosis
The constitutively expressed, chromosomally-encoded β-lactamase (BlaC) is the enzyme responsible for the intrinsic resistance to β-lactam antibiotics in Mycobacterium tuberculosis. Previous studies from this laboratory have shown that the enzyme exhibits an extended-spectrum phenotype, with very hig...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3750105/ https://ncbi.nlm.nih.gov/pubmed/23672214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400177y |
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