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Kinetics of Sulbactam Hydrolysis by β-Lactamases, and Kinetics of β-Lactamase Inhibition by Sulbactam

Sulbactam is one of four β-lactamase inhibitors in current clinical use to counteract drug resistance caused by degradation of β-lactam antibiotics by these bacterial enzymes. As a β-lactam itself, sulbactam is susceptible to degradation by β-lactamases. I investigated the Michaelis-Menten kinetics...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Yazar: Shapiro, Adam B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700308/
https://ncbi.nlm.nih.gov/pubmed/28971872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01612-17
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