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Hydrolysis and Inhibition Profiles of β-Lactamases from Molecular Classes A to D with Doripenem, Imipenem, and Meropenem
The stability of doripenem to hydrolysis by β-lactamases from molecular classes A to D was compared to the stability for imipenem and meropenem. Doripenem was stable to hydrolysis by extended-spectrum β-lactamases and AmpC type β-lactamases and demonstrated high affinity for the AmpC enzymes. For th...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798497/ https://ncbi.nlm.nih.gov/pubmed/19884379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01004-09 |
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