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Structure, Kinetic, and Chemical Mechanism of Isocitrate Dehydrogenase-1 from Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb) is the leading cause of death due to a bacterial infection. The success of the Mtb pathogen has largely been attributed to the nonreplicating, persistence phase of the life cycle, for which the glyoxylate shunt is required. In Escherichia coli flux through the shunt...

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Библиографические подробности
Главные авторы: Quartararo, Christine E., Hazra, Saugata, Hadi, Timin, Blanchard, John S.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706558/
https://ncbi.nlm.nih.gov/pubmed/23409873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400037w
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