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Structure, Kinetic, and Chemical Mechanism of Isocitrate Dehydrogenase-1 from Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb) is the leading cause of death due to a bacterial infection. The success of the Mtb pathogen has largely been attributed to the nonreplicating, persistence phase of the life cycle, for which the glyoxylate shunt is required. In Escherichia coli flux through the shunt...

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Detalhes bibliográficos
Main Authors: Quartararo, Christine E., Hazra, Saugata, Hadi, Timin, Blanchard, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706558/
https://ncbi.nlm.nih.gov/pubmed/23409873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400037w
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