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Solvent Isotope-induced Equilibrium Perturbation for Isocitrate Lyase
Isocitrate lyase (ICL) catalyzes the reversible retro-aldol cleavage of isocitrate to generate glyoxylate and succinate. ICL is the first enzyme of the glyoxylate shunt, which allows for the anaplerosis of citric acid cycle intermediates under nutrient limiting conditions. In Mycobacterium tuberculo...
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| Main Authors: | , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2013
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3905770/ https://ncbi.nlm.nih.gov/pubmed/24261638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4013319 |
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