Mutations in the small subunit of the Drosophila U2AF splicing factor cause lethality and developmental defects.
The essential eukaryotic pre-mRNA splicing factor U2AF (U2 small nuclear ribonucleoprotein auxiliary factor) is required to specify the 3' splice at an early step in spliceosome assembly. U2AF binds site-specifically to the intron polypyrimidine tract and recruits U2 small nuclear ribonucleoprotein...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
1996
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38384/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8816800/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.19.10333 |
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