RNA Binding Activity of Heterodimeric Splicing Factor U2AF: at Least One RS Domain Is Required for High-Affinity Binding

The pre-mRNA splicing factor U2AF (U2 small nuclear ribonucleoprotein particle [snRNP] auxiliary factor) plays a critical role in 3′ splice site selection. U2AF binds site specifically to the intron pyrimidine tract between the branchpoint and the 3′ splice site and targets U2 snRNP to the branch si...

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Bibliografske podrobnosti
Main Authors: Rudner, David Z., Breger, Kevin S., Kanaar, Roland, Adams, Melissa D., Rio, Donald C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
Teme:
Gene Expression
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC108985/
https://ncbi.nlm.nih.gov/pubmed/9632785
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