Dual Function for U2AF(35) in AG-Dependent Pre-mRNA Splicing
The splicing factor U2AF is required for the recruitment of U2 small nuclear RNP to pre-mRNAs in higher eukaryotes. The 65-kDa subunit of U2AF (U2AF(65)) binds to the polypyrimidine (Py) tract preceding the 3′ splice site, while the 35-kDa subunit (U2AF(35)) contacts the conserved AG dinucleotide at...
Guardat en:
| Publicat a: | Mol Cell Biol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2001
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99938/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11604503/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.22.7673-7681.2001 |
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