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Dual Function for U2AF(35) in AG-Dependent Pre-mRNA Splicing
The splicing factor U2AF is required for the recruitment of U2 small nuclear RNP to pre-mRNAs in higher eukaryotes. The 65-kDa subunit of U2AF (U2AF(65)) binds to the polypyrimidine (Py) tract preceding the 3′ splice site, while the 35-kDa subunit (U2AF(35)) contacts the conserved AG dinucleotide at...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC99938/ https://ncbi.nlm.nih.gov/pubmed/11604503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.22.7673-7681.2001 |
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