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SC35-mediated reconstitution of splicing in U2AF-depleted nuclear extract

Assembly of the mammalian spliceosome is known to proceed in an ordered fashion through several discrete complexes, but the mechanism of this assembly process may not be universal. In an early step, pre-mRNAs are committed to the splicing pathway through association with U1 small nuclear ribonucleop...

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Autores principales: MacMillan, Andrew M., McCaw, Patrick S., Crispino, John D., Sharp, Phillip A.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences of the USA 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC19256/
https://ncbi.nlm.nih.gov/pubmed/8990173
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