Dual Function for U2AF(35) in AG-Dependent Pre-mRNA Splicing

The splicing factor U2AF is required for the recruitment of U2 small nuclear RNP to pre-mRNAs in higher eukaryotes. The 65-kDa subunit of U2AF (U2AF(65)) binds to the polypyrimidine (Py) tract preceding the 3′ splice site, while the 35-kDa subunit (U2AF(35)) contacts the conserved AG dinucleotide at...

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書目詳細資料

發表在:	Mol Cell Biol
Principais autores:	Guth, Sabine, Tange, Thomas O/., Kellenberger, Esther, Valcárcel, Juan
格式:	Artigo
語言:	Inglês
出版:	Taylor & Francis 2001
主題:	Gene Expression
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99938/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11604503/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.22.7673-7681.2001
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