RNA Binding Activity of Heterodimeric Splicing Factor U2AF: at Least One RS Domain Is Required for High-Affinity Binding

The pre-mRNA splicing factor U2AF (U2 small nuclear ribonucleoprotein particle [snRNP] auxiliary factor) plays a critical role in 3′ splice site selection. U2AF binds site specifically to the intron pyrimidine tract between the branchpoint and the 3′ splice site and targets U2 snRNP to the branch si...

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Bibliografische Detailangaben

Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Rudner, David Z., Breger, Kevin S., Kanaar, Roland, Adams, Melissa D., Rio, Donald C.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1998
Schlagworte:	Gene Expression
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108985/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9632785/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.7.4004
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