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Polyomavirus Large T Antigen Binds Symmetrical Repeats at the Viral Origin in an Asymmetrical Manner

Polyomaviruses have repeating sequences at their origins of replication that bind the origin-binding domain of virus-encoded large T antigen. In murine polyomavirus, the central region of the origin contains four copies (P1 to P4) of the sequence G(A/G)GGC. They are arranged as a pair of inverted re...

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Main Authors: Harrison, Celia, Jiang, Tao, Banerjee, Pubali, Meinke, Gretchen, D'Abramo, Claudia M., Schaffhausen, Brian, Bohm, Andrew
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838254/
https://ncbi.nlm.nih.gov/pubmed/24109229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01740-13
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