Asymmetric Assembly of Merkel Cell Polyomavirus Large T-antigen Origin Binding Domains at the Viral Origin

The double-stranded DNA polyomavirus Merkel cell polyomavirus (MCV) causes Merkel cell carcinoma, an aggressive but rare human skin cancer that most often affects the immunosuppressed and elderly. As in other polyomaviruses, the large T-antigen of MCV recognizes the viral origin of replication by bi...

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Autori principali: Harrison, Celia J., Meinke, Gretchen, Kwun, Hyun Jin, Rogalin, Henry, Phelan, Paul J., Bullock, Peter A., Chang, Yuan, Moore, Patrick S., Bohm, Andrew
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104116/
https://ncbi.nlm.nih.gov/pubmed/21501625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.03.051
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