Nonstructural Protein σ1s Mediates Reovirus-Induced Cell Cycle Arrest and Apoptosis

Reovirus nonstructural protein σ1s is implicated in cell cycle arrest at the G(2)/M boundary and induction of apoptosis. However, the contribution of σ1s to these effects in an otherwise isogenic viral background has not been defined. To evaluate the role of σ1s in cell cycle arrest and apoptosis, w...

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Bibliographic Details
Main Authors: Boehme, Karl W., Hammer, Katharina, Tollefson, William C., Konopka-Anstadt, Jennifer L., Kobayashi, Takeshi, Dermody, Terence S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838159/
https://ncbi.nlm.nih.gov/pubmed/24067959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02080-13
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