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Nonstructural Protein σ1s Mediates Reovirus-Induced Cell Cycle Arrest and Apoptosis

Reovirus nonstructural protein σ1s is implicated in cell cycle arrest at the G(2)/M boundary and induction of apoptosis. However, the contribution of σ1s to these effects in an otherwise isogenic viral background has not been defined. To evaluate the role of σ1s in cell cycle arrest and apoptosis, w...

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Detalhes bibliográficos
Main Authors: Boehme, Karl W., Hammer, Katharina, Tollefson, William C., Konopka-Anstadt, Jennifer L., Kobayashi, Takeshi, Dermody, Terence S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838159/
https://ncbi.nlm.nih.gov/pubmed/24067959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02080-13
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