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Reovirus-Induced ς1s-Dependent G(2)/M Phase Cell Cycle Arrest Is Associated with Inhibition of p34(cdc2)

Serotype 3 reoviruses inhibit cellular proliferation by inducing a G(2)/M phase cell cycle arrest. Reovirus-induced G(2)/M phase arrest requires the viral S1 gene-encoded ς1s nonstructural protein. The G(2)-to-M transition represents a cell cycle checkpoint that is regulated by the kinase p34(cdc2)....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Poggioli, George J., Dermody, Terence S., Tyler, Kenneth L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC114978/
https://ncbi.nlm.nih.gov/pubmed/11462015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.16.7429-7434.2001
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