Safety and Immunogenicity of a Single Oral Dose of Recombinant Double Mutant Heat-Labile Toxin Derived from Enterotoxigenic Escherichia coli

Enterotoxigenic Escherichia coli (ETEC) is a primary cause of traveler's diarrhea for which there is no licensed vaccine. This phase 1 trial determined the safety and immunogenicity of a recombinantly produced double mutant heat-labile enterotoxin (dmLT) of ETEC. It was administered as a single...

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Detalhes bibliográficos
Main Authors: El-Kamary, Samer S., Cohen, Mitchell B., Bourgeois, A. Louis, Van De Verg, Lillian, Bauers, Nicole, Reymann, Mardi, Pasetti, Marcela F., Chen, Wilbur H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837789/
https://ncbi.nlm.nih.gov/pubmed/24049109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00464-13
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