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Significance of Enterotoxigenic Escherichia coli (ETEC) Heat-Labile Toxin (LT) Enzymatic Subunit Epitopes in LT Enterotoxicity and Immunogenicity

Enterotoxigenic Escherichia coli (ETEC) strains producing heat-labile toxin (LT) and/or heat-stable toxin (STa) are a top cause of children's diarrhea and travelers' diarrhea. Holotoxin-structured GM(1)-binding LT is a strong immunogen and an effective adjuvant, and can serve a carrier or...

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Bibliografiske detaljer
Udgivet i:Appl Environ Microbiol
Main Authors: Huang, Jiachen, Duan, Qiangde, Zhang, Weiping
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052278/
https://ncbi.nlm.nih.gov/pubmed/29802193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00849-18
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