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Double-targeting Using A TrkC-Ligand Conjugated To BODIPY-based PDT Agent

A molecule 1 (IY-IY-PDT) was designed to contain a fragment (IY-IY) that targets the TrkC receptor, and a photosensitizer that acts as an agent for photodynamic therapy (PDT). Molecule 1 had sub-micromolar photocytotoxicities to cells that were either engineered to stably express TrkC (NIH3T3-TrkC)...

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Autori principali: Kamkaew, Anyanee, Burgess, Kevin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837628/
https://ncbi.nlm.nih.gov/pubmed/24063347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm4012142
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