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Double-targeting Using A TrkC-Ligand Conjugated To BODIPY-based PDT Agent
A molecule 1 (IY-IY-PDT) was designed to contain a fragment (IY-IY) that targets the TrkC receptor, and a photosensitizer that acts as an agent for photodynamic therapy (PDT). Molecule 1 had sub-micromolar photocytotoxicities to cells that were either engineered to stably express TrkC (NIH3T3-TrkC)...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3837628/ https://ncbi.nlm.nih.gov/pubmed/24063347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm4012142 |
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