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Targeted PDT Agent Eradicates TrkC Expressing Tumors via Photodynamic Therapy (PDT)

[Image: see text] This contribution features a small molecule that binds TrkC (tropomyosin receptor kinase C) receptor that tends to be overexpressed in metastatic breast cancer cells but not in other breast cancer cells. A sensitizer for (1)O(2) production conjugated to this structure gives 1-PDT f...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Kue, Chin Siang, Kamkaew, Anyanee, Lee, Hong Boon, Chung, Lip Yong, Kiew, Lik Voon, Burgess, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291778/
https://ncbi.nlm.nih.gov/pubmed/25487316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp5005564
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