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Intracellular localization of 125I-labeled insulin in hepatocytes from intact rat liver.

We have shown that 125I-labeled insulin initially localizes to the plasma membrane of isolated rat hepatocytes. The ligand is subsequently internalized and preferentially localizes to lysosomal structures. Further, we have observed that labeled insulin localizes to regions of the cell rich in lysoso...

詳細記述

保存先:
書誌詳細
主要な著者: Carpentier, J L, Gorden, P, Barazzone, P, Freychet, P, Le Cam, A, Orci, L
フォーマット: Artigo
言語:Inglês
出版事項: 1979
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC383697/
https://ncbi.nlm.nih.gov/pubmed/288068
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