Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts.
Using a quantitative electron microscopic autoradiographic technique, we have localized the initial binding step of 125I-labeled epidermal growth factor (125I-EGF) to the plasma membrane of the human fibroblast. After initial binding, labeled EGF is internalized progressively by the cell in a time-...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1978
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336255/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/311005/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.10.5025 |
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