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Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts.

Using a quantitative electron microscopic autoradiographic technique, we have localized the initial binding step of 125I-labeled epidermal growth factor (125I-EGF) to the plasma membrane of the human fibroblast. After initial binding, labeled EGF is internalized progressively by the cell in a time-...

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Détails bibliographiques
Auteurs principaux: Gorden, P, Carpentier, J L, Cohen, S, Orci, L
Format: Artigo
Langue:Inglês
Publié: 1978
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC336255/
https://ncbi.nlm.nih.gov/pubmed/311005
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