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Affinity Purification of Human Factor H on Polypeptides Derived from Streptococcal M Protein: Enrichment of the Y402 Variant

Recent studies indicate that defective activity of complement factor H (FH) is associated with several human diseases, suggesting that pure FH may be used for therapy. Here, we describe a simple method to isolate human FH, based on the specific interaction between FH and the hypervariable region (HV...

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Detalhes bibliográficos
Main Authors: Nilsson, O. Rickard, Lannergård, Jonas, Morgan, B. Paul, Lindahl, Gunnar, Gustafsson, Mattias C. U.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836803/
https://ncbi.nlm.nih.gov/pubmed/24278416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081303
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