Loading...

δ(1)-Pyrroline-5-carboxylate reductase as a new target for therapeutics: inhibition of the enzyme from Streptococcus pyogenes and effects in vivo

Compounds able to interfere with amino acid biosynthesis have the potential to inhibit cell growth. In both prokaryotic and eukaryotic microorganisms, unless an ornithine cyclodeaminase is present, the activity of δ(1)-pyrroline-5-carboxylate (P5C) reductase is mandatory to proline production, and t...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Forlani, Giuseppe, Petrollino, Davide, Fusetti, Massimo, Romanini, Letizia, Nocek, Bogusław, Joachimiak, Andrzej, Berlicki, Łukasz, Kafarski, Paweł
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836680/
https://ncbi.nlm.nih.gov/pubmed/21744012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-011-0970-7
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!