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Mct8-Deficient Mice Have Increased Energy Expenditure and Reduced Fat Mass That Is Abrogated by Normalization of Serum T(3) Levels
Children with monocarboxylate transporter 8 (MCT8) deficiency lose weight, even when adequately nourished. Changes in serum markers of thyroid hormone (TH) action compatible with thyrotoxicosis suggested that this might be due to T(3) excess in peripheral tissues. Mct8-deficient mice (Mct8KO) replic...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Endocrine Society
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3836073/ https://ncbi.nlm.nih.gov/pubmed/24029243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-1150 |
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