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Mice deficient in MCT8 reveal a mechanism regulating thyroid hormone secretion

The mechanism of thyroid hormone (TH) secretion from the thyroid gland into blood is unknown. Humans and mice deficient in monocarboxylate transporter 8 (MCT8) have low serum thyroxine (T(4)) levels that cannot be fully explained by increased deiodination. Here, we have shown that Mct8 is localized...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Di Cosmo, Caterina, Liao, Xiao-Hui, Dumitrescu, Alexandra M., Philp, Nancy J., Weiss, Roy E., Refetoff, Samuel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929715/
https://ncbi.nlm.nih.gov/pubmed/20679730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42113
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