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Discovering Subgroups of Patients from DNA Copy Number Data Using NMF on Compacted Matrices

In the study of complex genetic diseases, the identification of subgroups of patients sharing similar genetic characteristics represents a challenging task, for example, to improve treatment decision. One type of genetic lesion, frequently investigated in such disorders, is the change of the DNA cop...

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Главные авторы: de Campos, Cassio P., Rancoita, Paola M. V., Kwee, Ivo, Zucca, Emanuele, Zaffalon, Marco, Bertoni, Francesco
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835832/
https://ncbi.nlm.nih.gov/pubmed/24278162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079720
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