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An integrated Bayesian analysis of LOH and copy number data

BACKGROUND: Cancer and other disorders are due to genomic lesions. SNP-microarrays are able to measure simultaneously both genotype and copy number (CN) at several Single Nucleotide Polymorphisms (SNPs) along the genome. CN is defined as the number of DNA copies, and the normal is two, since we have...

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Detalhes bibliográficos
Main Authors: Rancoita, Paola MV, Hutter, Marcus, Bertoni, Francesco, Kwee, Ivo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912301/
https://ncbi.nlm.nih.gov/pubmed/20550648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-321
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