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An integrated Bayesian analysis of LOH and copy number data

BACKGROUND: Cancer and other disorders are due to genomic lesions. SNP-microarrays are able to measure simultaneously both genotype and copy number (CN) at several Single Nucleotide Polymorphisms (SNPs) along the genome. CN is defined as the number of DNA copies, and the normal is two, since we have...

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主要な著者: Rancoita, Paola MV, Hutter, Marcus, Bertoni, Francesco, Kwee, Ivo
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912301/
https://ncbi.nlm.nih.gov/pubmed/20550648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-321
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