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An integrated Bayesian analysis of LOH and copy number data

BACKGROUND: Cancer and other disorders are due to genomic lesions. SNP-microarrays are able to measure simultaneously both genotype and copy number (CN) at several Single Nucleotide Polymorphisms (SNPs) along the genome. CN is defined as the number of DNA copies, and the normal is two, since we have...

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Main Authors: Rancoita, Paola MV, Hutter, Marcus, Bertoni, Francesco, Kwee, Ivo
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912301/
https://ncbi.nlm.nih.gov/pubmed/20550648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-321
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