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Bayesian DNA copy number analysis

BACKGROUND: Some diseases, like tumors, can be related to chromosomal aberrations, leading to changes of DNA copy number. The copy number of an aberrant genome can be represented as a piecewise constant function, since it can exhibit regions of deletions or gains. Instead, in a healthy cell the copy...

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Detalhes bibliográficos
Main Authors: Rancoita, Paola MV, Hutter, Marcus, Bertoni, Francesco, Kwee, Ivo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674052/
https://ncbi.nlm.nih.gov/pubmed/19133123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-10
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