A Process Similar to Autophagy Is Associated with Cytocidal Chloroquine Resistance in Plasmodium falciparum

Resistance to the cytostatic activity of the antimalarial drug chloroquine (CQ) is becoming well understood, however, resistance to cytocidal effects of CQ is largely unexplored. We find that PfCRT mutations that almost fully recapitulate P. falciparum cytostatic CQ resistance (CQR(CS)) as quantifie...

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Bibliografiske detaljer
Main Authors:	Gaviria, David, Paguio, Michelle F., Turnbull, Lindsey B., Tan, Asako, Siriwardana, Amila, Ghosh, Debasish, Ferdig, Michael T., Sinai, Anthony P., Roepe, Paul D.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science 2013
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3835802/ https://ncbi.nlm.nih.gov/pubmed/24278114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079059
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A Process Similar to Autophagy Is Associated with Cytocidal Chloroquine Resistance in Plasmodium falciparum

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