A Process Similar to Autophagy Is Associated with Cytocidal Chloroquine Resistance in Plasmodium falciparum

Resistance to the cytostatic activity of the antimalarial drug chloroquine (CQ) is becoming well understood, however, resistance to cytocidal effects of CQ is largely unexplored. We find that PfCRT mutations that almost fully recapitulate P. falciparum cytostatic CQ resistance (CQR(CS)) as quantifie...

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Hlavní autoři: Gaviria, David, Paguio, Michelle F., Turnbull, Lindsey B., Tan, Asako, Siriwardana, Amila, Ghosh, Debasish, Ferdig, Michael T., Sinai, Anthony P., Roepe, Paul D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835802/
https://ncbi.nlm.nih.gov/pubmed/24278114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079059
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