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A Process Similar to Autophagy Is Associated with Cytocidal Chloroquine Resistance in Plasmodium falciparum

Resistance to the cytostatic activity of the antimalarial drug chloroquine (CQ) is becoming well understood, however, resistance to cytocidal effects of CQ is largely unexplored. We find that PfCRT mutations that almost fully recapitulate P. falciparum cytostatic CQ resistance (CQR(CS)) as quantifie...

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Detalhes bibliográficos
Main Authors: Gaviria, David, Paguio, Michelle F., Turnbull, Lindsey B., Tan, Asako, Siriwardana, Amila, Ghosh, Debasish, Ferdig, Michael T., Sinai, Anthony P., Roepe, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835802/
https://ncbi.nlm.nih.gov/pubmed/24278114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079059
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