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A Rad53 Independent Function of Rad9 Becomes Crucial for Genome Maintenance in the Absence of the RecQ Helicase Sgs1

The conserved family of RecQ DNA helicases consists of caretaker tumour suppressors, that defend genome integrity by acting on several pathways of DNA repair that maintain genome stability. In budding yeast, Sgs1 is the sole RecQ helicase and it has been implicated in checkpoint responses, replisome...

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Библиографические подробности
Главные авторы: Nielsen, Ida, Bentsen, Iben Bach, Andersen, Anni H., Gasser, Susan M., Bjergbaek, Lotte
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835667/
https://ncbi.nlm.nih.gov/pubmed/24278365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081015
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