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DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1
To ensure proper replication and segregation of the genome, eukaryotic cells have evolved surveillance systems that monitor and react to impaired replication fork progression. In budding yeast, the intra-S phase checkpoint responds to stalled replication forks by downregulating late-firing origins,...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC175781/ https://ncbi.nlm.nih.gov/pubmed/12912929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg391 |
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