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DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1

To ensure proper replication and segregation of the genome, eukaryotic cells have evolved surveillance systems that monitor and react to impaired replication fork progression. In budding yeast, the intra-S phase checkpoint responds to stalled replication forks by downregulating late-firing origins,...

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Publicat a:EMBO J
Autors principals: Cobb, Jennifer A., Bjergbaek, Lotte, Shimada, Kenji, Frei, Christian, Gasser, Susan M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175781/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12912929/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg391
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