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DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1

To ensure proper replication and segregation of the genome, eukaryotic cells have evolved surveillance systems that monitor and react to impaired replication fork progression. In budding yeast, the intra-S phase checkpoint responds to stalled replication forks by downregulating late-firing origins,...

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Detalles Bibliográficos
Publicado en:EMBO J
Principais autores: Cobb, Jennifer A., Bjergbaek, Lotte, Shimada, Kenji, Frei, Christian, Gasser, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2003
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175781/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12912929/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg391
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