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Activation of K(Ca)3.1 by SKA-31 induces arteriolar dilatation and lowers blood pressure in normo- and hypertensive connexin40-deficient mice
BACKGROUND AND PURPOSE: The calcium-activated potassium channel K(Ca)3.1 is expressed in the vascular endothelium where its activation causes endothelial hyperpolarization and initiates endothelium-derived hyperpolarization (EDH)-dependent dilatation. Here, we investigated whether pharmacological ac...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Blackwell Publishing Ltd
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3834754/ https://ncbi.nlm.nih.gov/pubmed/23734697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12267 |
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