Naphtho[1,2-d]thiazol-2-ylamine (SKA-31), a New Activator of KCa2 and KCa3.1 Potassium Channels, Potentiates the Endothelium-Derived Hyperpolarizing Factor Response and Lowers Blood Pressure

Small-conductance (KCa2.1-2.3) and intermediate-conductance (KCa3.1) calcium-activated K(+) channels are critically involved in modulating calcium-signaling cascades and membrane potential in both excitable and nonexcitable cells. Activators of these channels constitute useful pharmacological tools...

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Detalhes bibliográficos
Main Authors: Sankaranarayanan, Ananthakrishnan, Raman, Girija, Busch, Christoph, Schultz, Tim, Zimin, Pavel I., Hoyer, Joachim, Köhler, Ralf, Wulff, Heike
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Pharmacology and Experimental Therapeutics 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2635097/
https://ncbi.nlm.nih.gov/pubmed/18955585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.051425
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