HMGB1 Acts in Synergy with Lipopolysaccharide in Activating Rheumatoid Synovial Fibroblasts via p38 MAPK and NF-κB Signaling Pathways

Synovial fibroblasts (SF) play a central role in the inflammatory and destructive process in rheumatoid arthritis (RA). High-mobility group box chromosomal protein 1 (HMGB1) or lipopolysaccharide (LPS) alone failed to induce significant changes in proliferation of cultured SF from RA patients, but p...

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Detalhes bibliográficos
Main Authors: He, Zheng-Wen, Qin, Yang-Hua, Wang, Zhi-Wei, Chen, Yan, Shen, Qian, Dai, Sheng-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834620/
https://ncbi.nlm.nih.gov/pubmed/24302816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/596716
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