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HMGB1–LPS complex promotes transformation of osteoarthritis synovial fibroblasts to a rheumatoid arthritis synovial fibroblast-like phenotype

It is generally believed that some inflammatory antigens can recognize Toll-like receptors on synovial fibroblasts (SFs) and then activate downstream signals, leading to the formation of RASFs and inducing rheumatoid arthritis (RA). The objective of the current work was to study on the hypothesis th...

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Autors principals: Qin, Y, Chen, Y, Wang, W, Wang, Z, Tang, G, Zhang, P, He, Z, Liu, Y, Dai, S-M, Shen, Q
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944262/
https://ncbi.nlm.nih.gov/pubmed/24556692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.48
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