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Dodine as a Protein Denaturant: The Best of Two Worlds?

Traditional denaturants such as urea and guanidinium ion unfold proteins in a cooperative “all-or-none” fashion. However, their high working concentration in combination with their strong absorption in the far ultraviolet region make it impossible to measure high quality circular dichroism or infrar...

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Main Authors: Gelman, Hannah, Perlova, Tatyana, Gruebele, Martin
格式: Artigo
語言:Inglês
出版: 2013
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834592/
https://ncbi.nlm.nih.gov/pubmed/23906507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp4028113
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