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Structure-Based Ligand Discovery Targeting Orthosteric and Allosteric Pockets of Dopamine Receptors
Small molecules targeting allosteric pockets of G protein–coupled receptors (GPCRs) have a great therapeutic potential for the treatment of neurologic and other chronic disorders. Here we performed virtual screening for orthosteric and putative allosteric ligands of the human dopamine D(3) receptor...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Pharmacology and Experimental Therapeutics
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3834142/ https://ncbi.nlm.nih.gov/pubmed/24021214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.088054 |
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