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Inhibition of Hedgehog and Androgen receptor signaling pathways produced synergistic suppression of castration-resistant prostate cancer progression
Metastatic prostate cancer (PCa) is initially treated with androgen ablation therapy, which causes regression of androgen-dependent tumors. However, these tumors eventually relapse resulting in recurrent castration-resistant prostate cancer (CRPC). Currently, there is no effective therapy for CRPC a...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3834015/ https://ncbi.nlm.nih.gov/pubmed/23989930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0278 |
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