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Androgen receptor abnormalities in castration-recurrent prostate cancer

The androgen receptor (AR) plays a critical role in prostate cancer (PCa) development and progression. Despite the success of androgen-deprivation therapy, remission occurs in almost all cases. This stage of the disease is called castration-recurrent PCa (CRPC). CRPC cells adapt to low circulating l...

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Bibliographic Details
Main Authors: Nacusi, Lucas P, Tindall, Donald J
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835169/
https://ncbi.nlm.nih.gov/pubmed/20228873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/eem.09.34
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